HONG KONG, Oct. 17, 2025 /PRNewswire/ — Explore Tokyo through the lens of its former Edo identity, where the concept of ‘iki’ – a subtle, effortless elegance that values authenticity, refinement and unpretentious style – was born. The Edo period, lasting roughly from 1600 to 1868, was known as a time of peace and stability, urbanization, economic growth and the flourishing of arts and culture. In this episode of CNN’s POV, follow International Correspondent Hanako Montgomery as she uncovers how ‘Tokyoites’ of today keep this urban code of understated cool alive through fashion, art and poetry.
Hanako begins by tracing how Edo’s merchant class expressed their wealth through subtle elegance in their fashion. At the Ichikura Kimono School, a kimono expert introduces the subtleties of dressing, pointing out how seemingly modest garments might conceal secret patterns or details. She then visits Ryukobo – a historic Tokyo atelier specialising in kumihimo – the traditional Japanese art of silk braiding used for making the cords that secure the sashes, or obis, of kimonos. A subtle yet elegant detail to a traditional ensemble, today, the brand is reimagining this refined craft for modern lifestyles, offering a wide range of products that carry the spirit of traditional elegance.
The concept of ‘iki’ extends beyond physical appearance and lives on through creative expression. Haiku, the succinct 17-syllable poetic form embodying much of the ‘iki’ spirit gained popularity during the Edo period. Today, 26-year-old Kei Iwata keeps the tradition alive through his award-winning poetry. Iwata, who’s passion for Haiku was first sparked by hip-hop battles, views haiku as a kind of music and has also collaborated with a wide range of musicians.
As an integral element of creative expression, ‘iki’ is deeply embedded in the artforms of the Edo period. Ukiyo-e are Japanese woodblock prints that depict everything from kabuki actors and sumo wrestlers to everyday scenes and landscapes. Noted art historian and curator of the Edo-Tokyo Museum, Shoko Haruki explains how the art reflects the urban imagination and coded elegance of ‘iki’. Today, the tradition is being revitalised through contemporary motifs and characters. Internationally recognised American artist Alex Dodge collaborates with craftsmen at the Adachi Institute to merge Edo-period printmaking techniques with modern imagery, breathing new life into this classic art genre, while Japanese graffiti artist, ESOW, is redefining urban cool by taking his art, a unique blend of skate and graffiti culture, to the streets.
POV trailer: https://bit.ly/3KMJhR2
POV images: https://bit.ly/3KYC5kB
Airtimes for 30-minute special:
Saturday, 18th October at 12:30pm HKT
Sunday, 19th October at 12.30am and 6pm HKT
Monday, 20th October at 11am HKT
About CNN International
CNN’s portfolio of news and information services is available in seven different languages across all major TV, digital and mobile platforms, reaching more than 379 million households around the globe. CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region, and Latin America and has a US presence that includes CNNgo. CNN Digital is a leading network for online news, mobile news and social media. CNN is at the forefront of digital innovation and continues to invest heavily in expanding its digital global footprint, with a suite of award-winning digital properties and a range of strategic content partnerships, commercialised through a strong data-driven understanding of audience behaviours. CNN has won multiple prestigious awards around the world for its journalism. Around 1,000 hours of long-form series, documentaries and specials are produced every year by CNNI’s non-news programming division. CNN has 36 editorial offices and more than 1,100 affiliates worldwide through CNN Newsource. CNN International is a Warner Bros. Discovery company.
HONG KONG, Oct. 17, 2025 /PRNewswire/ — Explore Tokyo through the lens of its former Edo identity, where the concept of ‘iki’ – a subtle, effortless elegance that values authenticity, refinement and unpretentious style – was born. The Edo period, lasting roughly from 1600 to 1868, was known as a time of peace and stability, urbanization, economic growth and the flourishing of arts and culture. In this episode of CNN’s POV, follow International Correspondent Hanako Montgomery as she uncovers how ‘Tokyoites’ of today keep this urban code of understated cool alive through fashion, art and poetry.
Hanako begins by tracing how Edo’s merchant class expressed their wealth through subtle elegance in their fashion. At the Ichikura Kimono School, a kimono expert introduces the subtleties of dressing, pointing out how seemingly modest garments might conceal secret patterns or details. She then visits Ryukobo – a historic Tokyo atelier specialising in kumihimo – the traditional Japanese art of silk braiding used for making the cords that secure the sashes, or obis, of kimonos. A subtle yet elegant detail to a traditional ensemble, today, the brand is reimagining this refined craft for modern lifestyles, offering a wide range of products that carry the spirit of traditional elegance.
The concept of ‘iki’ extends beyond physical appearance and lives on through creative expression. Haiku, the succinct 17-syllable poetic form embodying much of the ‘iki’ spirit gained popularity during the Edo period. Today, 26-year-old Kei Iwata keeps the tradition alive through his award-winning poetry. Iwata, who’s passion for Haiku was first sparked by hip-hop battles, views haiku as a kind of music and has also collaborated with a wide range of musicians.
As an integral element of creative expression, ‘iki’ is deeply embedded in the artforms of the Edo period. Ukiyo-e are Japanese woodblock prints that depict everything from kabuki actors and sumo wrestlers to everyday scenes and landscapes. Noted art historian and curator of the Edo-Tokyo Museum, Shoko Haruki explains how the art reflects the urban imagination and coded elegance of ‘iki’. Today, the tradition is being revitalised through contemporary motifs and characters. Internationally recognised American artist Alex Dodge collaborates with craftsmen at the Adachi Institute to merge Edo-period printmaking techniques with modern imagery, breathing new life into this classic art genre, while Japanese graffiti artist, ESOW, is redefining urban cool by taking his art, a unique blend of skate and graffiti culture, to the streets.
POV trailer: https://bit.ly/3KMJhR2
POV images: https://bit.ly/3KYC5kB
Airtimes for 30-minute special:
Saturday, 18th October at 12:30pm HKT
Sunday, 19th October at 12.30am and 6pm HKT
Monday, 20th October at 11am HKT
About CNN International
CNN’s portfolio of news and information services is available in seven different languages across all major TV, digital and mobile platforms, reaching more than 379 million households around the globe. CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region, and Latin America and has a US presence that includes CNNgo. CNN Digital is a leading network for online news, mobile news and social media. CNN is at the forefront of digital innovation and continues to invest heavily in expanding its digital global footprint, with a suite of award-winning digital properties and a range of strategic content partnerships, commercialised through a strong data-driven understanding of audience behaviours. CNN has won multiple prestigious awards around the world for its journalism. Around 1,000 hours of long-form series, documentaries and specials are produced every year by CNNI’s non-news programming division. CNN has 36 editorial offices and more than 1,100 affiliates worldwide through CNN Newsource. CNN International is a Warner Bros. Discovery company.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
CNN’s POV uncovers how the Edo period aesthetic ideal of ‘iki’ shapes modern Tokyo
Illumina’s up-and-coming constellation innovation delivers accuracy, speed, and ease of use in trial by GeneDx
Constellation outperformed orthogonal methods in identifying select difficult-to-map variants
SAN DIEGO, Oct. 17, 2025 /PRNewswire/ — Illumina, Inc. (NASDAQ: ILMN) announced that GeneDx, a leader in genetic testing for rare diseases, is piloting Illumina’s emerging constellation mapped read technology, evaluating its performance on regions of the genome that traditional short-read technologies historically have not resolved. GeneDx’s early results illustrate the ability of constellation to rapidly identify hard-to-detect variants implicated in rare disease. GeneDx’s Director of Laboratory Innovation Joe Devaney presented on the company’s early experiences with the constellation technology at the American Society for Human Genetics (ASHG) Annual Meeting in Boston.
“Illumina is unlocking ways to access the most difficult regions of the genome, as we simultaneously lead the industry into a new era of multiomics,” said Steve Barnard, chief technology officer of Illumina. “Genomic insights remain critical to advance diagnosis and treatment for many rare and complex diseases, and our constellation technology provides the research insights that enable our customers to tackle these challenging conditions on the platforms they already use.”
For the pilot project, GeneDx used its fleet of NovaSeq X Plus Systems with constellation kits to evaluate 160 DNA samples from individuals with known genetic disease. GeneDx compared samples run with constellation to orthogonal methods, like long-read sequencing, arrays, and multiplex ligation-dependent probe amplification. Constellation was able to accurately uncover repeat expansions, complex structural variants, and elusive regions of the genome, demonstrating the technology’s ability to meet or exceed the capabilities of established alternative methods.
Constellation was able to quickly identify difficult-to-detect, biologically relevant variants, including those in:
DMPK, which is associated with myotonic dystrophy and is caused by large repeat expansions; SMN1, which is associated with spinal muscular atrophy but is difficult to detect based on the highly homologous SMN2 gene; NCF1, which is associated with an inherited immune disorder called chronic granulomatous disease, but is challenging to identify due to highly homologous pseudogenes; and Mosaic aneuploidy, which causes some cells to have chromosomal abnormalities. It can cause developmental delays and increase the risk of some childhood cancers.
Deep and rapid insights from whole-genome sequencing can help researchers understand and better identify potential treatments for these hard-to-diagnose conditions. Constellation is emerging as a flexible solution that performs accurately across a variety of sample types—including buccal, blood, and chorionic villus (prenatal) samples—and extraction kits.
“Innovation and patient centricity fuel everything we do at GeneDx,” said Devaney. “We’re continually looking to advance research and clinical genomics to drive the future of precision medicine and better health outcomes for all. The level of detail we can achieve with constellation provides promising insight into some of the world’s most complex and difficult-to-diagnose diseases. By combining speed, simplicity, and scientific rigor, this technology has the potential to transform how we understand rare disease, helping improve how we diagnose and treat patients.”
How constellation mapped read technology works
Constellation builds on Illumina’s industry-leading sequencing-by-synthesis chemistry to unlock long-range genomic insights with unmatched simplicity. Long sequences of unfragmented DNA are applied directly to the flow cell for cluster generation. This on-flow-cell library prep eliminates manual library preparation and enables a streamlined workflow with fewer validation steps. Proprietary informatics extract long-distance data from the proximity of resulting neighboring clusters. This novel data allows for accurate mapping of homologous or repetitive regions of the genome, resolving mapping ambiguities, and resolving complex variant types.
Constellation was first introduced at the 2024 ASHG conference. The first commercially available product based on constellation technology is slated for release in the first half of 2026, compatible with the NovaSeq X Series.
Joe Devaney presented the results of GeneDx’s expanded, 160-sample study with constellation on October 15 at the ASHG Annual Meeting in Boston. His talk, “Mapping the Future of Whole Genome Sequencing with Illumina Constellation Technology,” was held in Room 153ABC from 12:00 PM to 1:00 PM ET. To preregister for access to the replay, follow this link. You can see all of Illumina’s multiomics solutions that are in development or commercially available here.
Use of forward-looking statements
This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) challenges inherent in developing and launching new products and services, including modifying and scaling manufacturing operations, and reliance on third-party suppliers for critical components; (ii) our ability to manufacture robust instrumentation and consumables; and (iii) the acceptance by customers of our newly launched products, which may or may not meet our and their expectations, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts’ expectations, or to provide interim reports or updates on the progress of the current quarter.
About Illumina
Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.
About GeneDx
GeneDx (Nasdaq: WGS) is the global leader in rare disease diagnosis, transforming the way medicine is practiced by making genomics the starting point for health, not the last resort. We bring together unmatched clinical expertise, advanced technology, and the power of GeneDx Infinity™ – the largest rare disease dataset – built over 25 years from millions of genomic tests and deep clinical insights. This unparalleled foundation powers our ExomeDx™ and GenomeDx™ tests, giving clinicians the highest likelihood of delivering a timely, accurate diagnosis. GeneDx is shaping the future of healthcare by moving the standard of care from sick care to proactive healthcare. While our roots are in rare disease diagnosis, our commitment extends beyond – growing with the families we serve – as a trusted partner at every stage of life. For more information, visit genedx.com and connect with us on LinkedIn, Facebook, and Instagram.
Illumina’s up-and-coming constellation innovation delivers accuracy, speed, and ease of use in trial by GeneDx
Constellation outperformed orthogonal methods in identifying select difficult-to-map variants
SAN DIEGO, Oct. 17, 2025 /PRNewswire/ — Illumina, Inc. (NASDAQ: ILMN) announced that GeneDx, a leader in genetic testing for rare diseases, is piloting Illumina’s emerging constellation mapped read technology, evaluating its performance on regions of the genome that traditional short-read technologies historically have not resolved. GeneDx’s early results illustrate the ability of constellation to rapidly identify hard-to-detect variants implicated in rare disease. GeneDx’s Director of Laboratory Innovation Joe Devaney presented on the company’s early experiences with the constellation technology at the American Society for Human Genetics (ASHG) Annual Meeting in Boston.
“Illumina is unlocking ways to access the most difficult regions of the genome, as we simultaneously lead the industry into a new era of multiomics,” said Steve Barnard, chief technology officer of Illumina. “Genomic insights remain critical to advance diagnosis and treatment for many rare and complex diseases, and our constellation technology provides the research insights that enable our customers to tackle these challenging conditions on the platforms they already use.”
For the pilot project, GeneDx used its fleet of NovaSeq X Plus Systems with constellation kits to evaluate 160 DNA samples from individuals with known genetic disease. GeneDx compared samples run with constellation to orthogonal methods, like long-read sequencing, arrays, and multiplex ligation-dependent probe amplification. Constellation was able to accurately uncover repeat expansions, complex structural variants, and elusive regions of the genome, demonstrating the technology’s ability to meet or exceed the capabilities of established alternative methods.
Constellation was able to quickly identify difficult-to-detect, biologically relevant variants, including those in:
DMPK, which is associated with myotonic dystrophy and is caused by large repeat expansions; SMN1, which is associated with spinal muscular atrophy but is difficult to detect based on the highly homologous SMN2 gene; NCF1, which is associated with an inherited immune disorder called chronic granulomatous disease, but is challenging to identify due to highly homologous pseudogenes; and Mosaic aneuploidy, which causes some cells to have chromosomal abnormalities. It can cause developmental delays and increase the risk of some childhood cancers.
Deep and rapid insights from whole-genome sequencing can help researchers understand and better identify potential treatments for these hard-to-diagnose conditions. Constellation is emerging as a flexible solution that performs accurately across a variety of sample types—including buccal, blood, and chorionic villus (prenatal) samples—and extraction kits.
“Innovation and patient centricity fuel everything we do at GeneDx,” said Devaney. “We’re continually looking to advance research and clinical genomics to drive the future of precision medicine and better health outcomes for all. The level of detail we can achieve with constellation provides promising insight into some of the world’s most complex and difficult-to-diagnose diseases. By combining speed, simplicity, and scientific rigor, this technology has the potential to transform how we understand rare disease, helping improve how we diagnose and treat patients.”
How constellation mapped read technology works
Constellation builds on Illumina’s industry-leading sequencing-by-synthesis chemistry to unlock long-range genomic insights with unmatched simplicity. Long sequences of unfragmented DNA are applied directly to the flow cell for cluster generation. This on-flow-cell library prep eliminates manual library preparation and enables a streamlined workflow with fewer validation steps. Proprietary informatics extract long-distance data from the proximity of resulting neighboring clusters. This novel data allows for accurate mapping of homologous or repetitive regions of the genome, resolving mapping ambiguities, and resolving complex variant types.
Constellation was first introduced at the 2024 ASHG conference. The first commercially available product based on constellation technology is slated for release in the first half of 2026, compatible with the NovaSeq X Series.
Joe Devaney presented the results of GeneDx’s expanded, 160-sample study with constellation on October 15 at the ASHG Annual Meeting in Boston. His talk, “Mapping the Future of Whole Genome Sequencing with Illumina Constellation Technology,” was held in Room 153ABC from 12:00 PM to 1:00 PM ET. To preregister for access to the replay, follow this link. You can see all of Illumina’s multiomics solutions that are in development or commercially available here.
Use of forward-looking statements
This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) challenges inherent in developing and launching new products and services, including modifying and scaling manufacturing operations, and reliance on third-party suppliers for critical components; (ii) our ability to manufacture robust instrumentation and consumables; and (iii) the acceptance by customers of our newly launched products, which may or may not meet our and their expectations, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts’ expectations, or to provide interim reports or updates on the progress of the current quarter.
About Illumina
Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.
About GeneDx
GeneDx (Nasdaq: WGS) is the global leader in rare disease diagnosis, transforming the way medicine is practiced by making genomics the starting point for health, not the last resort. We bring together unmatched clinical expertise, advanced technology, and the power of GeneDx Infinity™ – the largest rare disease dataset – built over 25 years from millions of genomic tests and deep clinical insights. This unparalleled foundation powers our ExomeDx™ and GenomeDx™ tests, giving clinicians the highest likelihood of delivering a timely, accurate diagnosis. GeneDx is shaping the future of healthcare by moving the standard of care from sick care to proactive healthcare. While our roots are in rare disease diagnosis, our commitment extends beyond – growing with the families we serve – as a trusted partner at every stage of life. For more information, visit genedx.com and connect with us on LinkedIn, Facebook, and Instagram.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Illumina constellation mapped read technology uncovers hard-to-see genomic insights in GeneDx pilot
AloJapan.com